Yue Ge
US Environmental Protection Agency, USA
Title : Environment Pollution and Public Health: Current Status and Trends of Environmental Research
Abstract :

Human are exposed to a variety of environmental chemicals or pollutants. Given the large number and complexity of environmental chemicals or pollutants, the current scientific approaches for assessment of the environmental pollution status using chemical analysis of air, water, soil, and other environmental samples alone may not offer meaningful assessment of the pollution status of a particular ecosystem and the risk of the pollution to human health. Complex environmental pollution problems can not be solved either by modern environmental engineering or technology alone. Integration of a variety of environmental sciences including basic environmental research, environmental engineering, ecology, and management on social and economic activities will provide effective solutions to complex environmental problems. My presentation will provide an overview of environmental pollution from an environmental health perspective.  Key environmental technologies and approaches will be described, and examples of the application of these technologies and methods to understanding adverse health effects of environmental chemical exposures will be presented. Opportunities for future studies of environmental health and disease will also be discussed.

Biography :

Yue received his Ph.D. in Proteomics at the University of Michigan, Ann Arbor, USA, where he investigated biological mechanisms of Duchenn Muscular Dystrophy by identifying and characterizing protein targets, biomarkers and signaling pathways associated with the disease using functional proteomic approaches. Prior to his Ph.D. studies, he had worked in Walther Oncology Center, Indiana University for four years. His research focused on identification of gene mutations and genetic polymorphisms associated with hypertension, and characterization of cytokine gene expression in human stem and progenitor cells for gene therapy. Following completion of his Ph.D. studies, Yue moved to Department of Proteomics at Invitrogen Inc., where he worked as a lead scientist to develop proteomics technologies and to identify breast cancer biomarkers using the Multiplexed Proteomics Technology Platform built within the research team. As a project leader for bioassay development, Yue also developed many quantitative protein assays for the detection and quantification of disease biomarkers. His work resulted in two patents and a series of bioassays that are being wildly used in biomedical research. After that, Yue took the position of Principal Investigator at US Environmental Protection Agency to lead environmental proteomics research. His laboratory is working in the emerging field of toxicoproteomics. Utilizing improved toxicoproteomic technologies developed by his research team and others to decipher mechanisms and modes of action of chemical-induced carcinogenesis and identify protein biomarkers of exposure, toxicity and effect have been his major research interests. To date, he has published about 25 peer-reviewed scientific papers and 40 abstracts that have been presented in national and international conferences. With regard to service to the broader scientific community, Yue has served as the chair for several international conferences such as 2007 American Electrophoresis Society Annual Meeting, 2008 SETAC European Meeting, and 2008 SETAC World Congress. He has also been an invited speaker for many national and international scientific conferences. As for editorial service, he has consistently reviewed scientific manuscripts s for several proteomics and environmental science journals such as “electrophoresis”, “Proteomics”, “Journal of Proteome Research”, “Oxford Genomics and Proteomics”, “Journal of Environmental Toxicology and Chemistry”, and “Toxicology Letters.”

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